Publications
2021
Otto Stern’s Legacy in Quantum Optics: Matter Waves and Deflectometry
S. Gerlich, Y. Y. Fein, A. Shayeghi, V. Köhler, M. Mayor, M. Arndt*
Molecular Beams in Physics and Chemistry (Eds. B. Friedrich, H. Schmidt-Böcking), Springer, Cham. , 2021, pp. 547-573
2020
Matterwave interference and deflection of tripeptides decorated with fluorinated alkyl chains
J. Schätti, V. Köhler, M. Mayor, Y. Y. Fein, P. Geyer, L. Mairhofer, S. Gerlich, M. Arndt*
J. Mass Spectrom. 2020, 55, e4514
2019
Neutralization of insulin by photocleavage under high vacuum
J. Schätti, M. Kriegleder, M. Debiossac, M. Kerschbaum, P. Geyer, M. Mayor, M. Arndt*, V. Köhler*
Chem. Commun. 2019, 55, 12507-12510
2018
Artificial Metalloenzymes: Reaction Scope and Optimization Strategies
F. Schwizer, Y. Okamoto, T. Heinisch, Y. Gu, M. M. Pellizzoni, V. Lebrun, R. Reuter, V. Köhler, J. C. Lewis*, T. R. Ward*
Chem. Rev. 2018, 118, 142-231
Pushing the mass limit for intact launch and photoionization of large neutral biopolymers
J. Schätti, P. Rieser, U. Sezer, G. Richter, P. Geyer, G. G. Rondina, D. Häussinger, M. Mayor, A. Shayeghi, V. Köhler*, M. Arndt*
Commun. Chem. 2018, 1, 93
Tailored photocleavable peptides: fragmentation and neutralization pathways in high vacuum
M. Debiossac, J. Schätti, M. Kriegleder, P. Geyer, A. Shayeghi, M. Mayor, M. Arndt*, V. Köhler*
Phys. Chem. Chem. Phys. 2018, 20, 11412-11417
2017
Tailoring the volatility and stability of oligopeptides
J. Schätti, U. Sezer, S. Pedalino, J. Cotter, M. Arndt*, M. Mayor, V. Köhler*
J. Mass Spectrom. 2017, 52, 550-556
2016
An NAD(P)H-dependent artificial transfer hydrogenase for multienzymatic cascades
Y. Okamoto, V. Köhler, T. R. Ward*
J. Am. Chem. Soc. 2016, 138, 5781-5784
Efficient in situ regeneration of NADH mimics by an artificial metalloenzyme
Y. Okamoto, V. Köhler, C. E. Paul, F. Hollmann, T. R. Ward*
ACS Catal. 2016, 6, 3553-3557
Upregulation of an artificial zymogen by proteolysis
Z. Liu, V. Lebrun, T. Kitanosono, H. Mallin, V. Köhler, D. Häussinger, D. Hilvert, S. Kobayashi, T. R. Ward*
Angew. Chem. Int. Ed. 2016, 55, 11587-11590
Cascade Reactions
M. Dürrenberger, V. Köhler, Y. M. Wilson, D. Ghislieri, L. Knörr, N. J. Turner, T. R. Ward
Practical Methods for Biocatalysis and Biotransformations 3 (Eds. J. Whittall, P. W. Sutton, W. Kroutil), J. Wiley & Sons Ltd., Chichester, 2016, pp. 213-252
2015
Editorial overview: Biocatalysis and biotransformation: Bio-inspired, bio-based and bio-linked catalysis
T. R. Ward*, V. Köhler
Curr. Opin. Chem. Biol. 2015, 25, 5-6
Artificial metalloenzymes for the diastereoselective reduction of NAD+ to NAD2H
T. Quinto, D. Häussinger, V. Köhler, T. R. Ward*
Org. Biomol. Chem. 2015, 13, 357-360
Artificial concurrent catalytic processes involving enzymes
V. Köhler*, N. J. Turner*
Chem. Commun. 2015, 51, 450-464
Improving the catalytic performance of an artificial metalloenzyme by computational design
T. Heinisch, M. Pellizzoni, M. Dürrenberger, C. E. Tinberg, V. Köhler, J. Klehr, D. Häussinger, D. Baker*, T. R. Ward*
J. Am. Chem. Soc. 2015, 137, 10414-10419
2014
Expanding the chemical diversity in artificial imine reductases based on the biotin–streptavidin technology
T. Quinto, F. Schwizer, J. M. Zimbron, A. Morina, V. Köhler, T. R. Ward*
ChemCatChem 2014, 6, 1010-1014
Recent trends in biomimetic NADH regeneration
T. Quinto, V. Köhler, T. R. Ward*
Top. Catal. 2014, 57, 321-331
Highlight: Concurrent cross metathesis and enzymatic oxidation: Enabling off‐equilibrium transformations
V. Köhler*, T. R. Ward
ChemCatChem 2014, 6, 2191-2193
An artificial imine reductase based on the ribonuclease S scaffold
M. Genz, V. Köhler, M. Krauss, D. Singer, R. Hoffmann, T. R. Ward, N. Sträter*
ChemCatChem 2014, 6, 736-740
2013
Genetic optimization of the catalytic efficiency of artificial imine reductases based on biotin–streptavidin technology
F. Schwizer, V. Köhler, M. Dürrenberger, L. Knörr, T. R. Ward*
ACS Catal. 2013, 3, 1752-1755
Synthetic cascades are enabled by combining biocatalysts with artificial metalloenzymes
V. Köhler, Y. Wilson, M. Dürrenberger, D. Ghislieri, E. Churakova, T. Quinto, L. Knörr, D. Häussinger, F. Hollmann*, N. Turner*, T. R. Ward*
Nat. Chem. 2013, 5, 93-99
2012
Selective Oxidation
V. Köhler, B. Groenendaal, K. R. Bailey, A. Znabet, J. Raferty, M. Helliwell, N. J. Turner, K. Geitner, U. T. Bornscheuer, G. de Gonzalo
Practical Methods for Biocatalysis and Biotransformations 2 (Eds. J. Whittall, P. W. Sutton), J. Wiley & Sons Ltd., Chichester, 2012, pp. 181-202
2011
Chimeric self-sufficient P450cam-RhFRed biocatalysts with broad substrate scope
A. Robin, V. Köhler, A. Jones, A. Ali, P. P. Kelly, E. O'Reilly, N. J. Turner, S. L. Flitsch*
Beilstein J. Org. Chem. 2011, 7, 1494-1498
Cytochromes P450 as useful biocatalysts: addressing the limitations
E. O'Reilly, V. Köhler, S. L. Flitsch*, N. J. Turner*
Chem. Commun. 2011, 47, 2490-2501
OsO4⋅ Streptavidin: A Tunable Hybrid Catalyst for the Enantioselective cis‐Dihydroxylation of Olefins
V. Köhler, J. Mao, T. Heinisch, A. Pordea, A. Sardo, Y. M. Wilson, L. Knörr, M. Creus, J. C. Prost, T. Schirmer*, T. R. Ward*
Angew. Chem. Int. Ed. 2011, 50, 10863-10866
2010
Highly stereoselective synthesis of substituted prolyl peptides using a combination of biocatalytic desymmetrization and multicomponent reactions
A. Znabet, E. Ruijter, F. J. de Kanter, V. Köhler, M. Helliwell, N. J. Turner, R. V. Orru*
Angew. Chem. Int. Ed. 2010, 49, 5289-5292
Protein-based hybrid catalysts — design and evolution
V. Köhler, Y. M. Wilson, C. Lo, A. Sardo, T. R. Ward*
Curr. Opin. Biotechnol. 2010, 21, 744-752
Highlight: Design of a functional nitric oxide reductase within a myoglobin scaffold
V. Köhler, T. R. Ward*
ChemBioChem 2010, 11, 1049-1051
Enantioselective biocatalytic oxidative desymmetrization of substituted pyrrolidines
V. Köhler, K. R. Bailey, A. Znabet, J. Raftery, M. Helliwell, N. J. Turner*
Angew. Chem. Int. Ed. 2010, 49, 2182-2184
2008
Chiral boron‐bridged bisoxazoline (Borabox) ligands: Structures and reactivities of Pd and Cu complexes
V. Köhler, C. Mazet, A. Toussaint, K. Kulicke, D. Häussinger, M. Neuburger, S. Schaffner, S. Kaiser, A. Pfaltz*
Chemistry – Eur. J. 2008, 14, 8530-8539
The structure of monoamine oxidase from Aspergillus niger provides a molecular context for improvements in activity obtained by directed evolution
K. E. Atkin, R. Reiss, V. Koehler, K. R. Bailey, S. Hart, J. P. Turkenburg, N. J. Turner, A. M. Brzozowski*, G. Grogan*
J. Mol. Biol. 2008, 384, 1218-1231
2006
Kinetic resolution of diols and pyridyl alcohols by Cu (II)(borabox)-catalyzed acylation
C. Mazet, S. Roseblade, V. Köhler, A. Pfaltz*
Org. Lett. 2006, 8, 1879-1882
Synthesis of boron-bridged anionic C2-symmetric bisoxazolines and their application in asymmetric catalysis
C. Mazet, V. Köhler, S. Roseblade, A. Toussaint, A. Pfaltz*
Chimia 2006, 60, 195-198
2005
Chiral boron-bridged bisoxazolines: Readily available anionic ligands for asymmetric catalysis
C. Mazet, V. Köhler, A. Pfaltz*
Angew. Chem. Int. Ed. 2005, 44, 4888-4891